![[Pasted image 20250111161558.png]] ## Physiologic effects of aging on the skin - ↘ cell replacement and recruitment - ↘ injury response - ↘ immune responsiveness - ↘ functional capacity - ↘ barrier function - ↘ chemical clearance - ↘ sensory perception - ↘ vascular responsiveness - ↘ thermoregulation - ↘ production - ↘ sweat - ↘ Vitamin D ![[Pasted image 20250111162438.png | Histologic findings in aging skin]] ## Photoaging (actinic changes) - Exam findings: - rhytids - laxity - pigmentary mottling ![[Pasted image 20250111162151.png | Figure 2: Histologic findings of photoaging]] #basicscience #Plastics